This cell 3D model shows two cells you can turn, cut open and click: an animal cell, which is a eukaryotic cell, and an E. coli bacterium, which is a prokaryotic cell. Click any organelle for its name, size and job, or switch to Compare to see both cells at true relative scale.
How to use the cell model
The model opens on the animal cell with a wedge cut out, so you see the organelles inside. Drag to rotate, scroll to zoom and click any part to open its card. The camera flies to the part and the other parts fade back.
- The switch above the model picks the eukaryote (an animal cell) or the prokaryote (an E. coli bacterium).
- The Parts tab lists every organelle by job and has the switch that turns labels on. Hover a name to light it up in the cell.
- The View tab sets how the cell is cut open, spreads the parts apart or shows only the part you picked.
- Compare puts both cells side by side with a scale bar. Quiz asks you to click organelles and match them to their functions.
Parts of an animal cell and what they do
An animal cell is a eukaryotic cell. Its DNA sits inside a nucleus, and its work is divided among membrane-bound organelles. An animal cell has no cell wall and no chloroplasts, so the plasma membrane is its outer edge. A flat animal cell diagram shows each organelle in a different color. The 3D model shows how they sit around and inside each other.
Each organelle name below is a link that opens its card in the model.
| Organelle | What it does | Size |
|---|---|---|
| Plasma membrane | Separates the cell from its surroundings and controls what passes | 5 to 10 nm thick |
| Cytoplasm | Jelly-like fluid that holds the organelles; 70 to 80 percent water | 10 to 100 µm across |
| Nucleus | Stores the DNA and directs protein synthesis | 5 to 10 µm across |
| Nucleolus | Assembles ribosome subunits | 1.8 µm across |
| Nuclear pore | Controls traffic between the nucleus and the cytoplasm | 97 to 120 nm across |
| Ribosome | Reads messenger RNA and builds proteins | 20 to 30 nm across |
| Rough ER | Makes and folds proteins for membranes and export | 60 to 100 nm thick |
| Smooth ER | Makes lipids, detoxifies chemicals and stores calcium | 60 to 100 nm across |
| Golgi apparatus | Modifies, sorts and ships proteins | 0.7 to 1.1 µm across |
| Vesicle | Carries cargo between organelles | 30 to 80 nm across |
| Mitochondrion | Makes ATP from food molecules | 0.5 to 2 µm long |
| Lysosome | Digests waste and worn-out cell parts | 0.1 to 1.2 µm across |
| Peroxisome | Breaks down fatty acids and handles hydrogen peroxide | 0.1 to 1 µm across |
| Centrosome | Organizes the microtubules | 0.2 to 0.5 µm |
| Microtubule | Hollow track for vesicles; holds shape | 23 to 25 nm across |
| Actin filament | Thin fibre that shapes the cell surface and lets cells move | 7 nm across |
| Intermediate filament | Rope-like fibre that bears tension | 8 to 10 nm across |
| Microvilli | Fold the membrane to add surface for absorbing nutrients | 1 to 6 µm long |
Mitochondria: the powerhouse of the cell
Mitochondria are oval organelles with two membranes. The outer membrane forms the boundary. The inner membrane folds into shelves called cristae, and the space those folds enclose is the matrix. In the model the cristae show through the cut. A typical mitochondrion is about 0.5 µm across and up to 2 µm long.
Mitochondria make ATP, the molecule a cell spends as energy. That is why textbooks call them the powerhouse of the cell. The folds matter because the ATP-making machinery sits on the inner membrane, and more folds mean more room for it.
Cells that burn a lot of energy carry a lot of mitochondria. A rat liver cell holds about 1,665 of them, and together they fill about 22 percent of the cell’s volume. A HeLa cell has 383 to 882. Mitochondria also keep a small amount of their own DNA, a remnant of their origin as free-living bacteria that moved into a larger cell.
The cell membrane (plasma membrane)
The cell membrane is a phospholipid bilayer with proteins embedded in it. Two layers of lipid make a sheet only 5 to 10 nm thick. A red blood cell’s membrane is about 7.5 nm thick, around 1/1,000 of the cell’s 8 µm width.
The membrane controls what enters and leaves. Nutrients come in, waste goes out and signals arrive. The embedded proteins work as channels, pumps and receptors, and the lipid bilayer blocks most other traffic. Select the membrane in the model and the other parts dim so you can see the boundary as one continuous surface. The finger-like microvilli are folds of this same membrane.
Every cell has a plasma membrane, including bacteria. In E. coli it is the inner membrane of a two-membrane envelope, and it carries out jobs that mitochondria do in your cells. For how membranes move molecules, see types of membrane transport and types of membrane proteins.
Golgi apparatus
The Golgi apparatus is a stack of flattened membrane sacs called cisternae. In mammalian cells a stack holds 4 to 11 cisternae, and each is 0.7 to 1.1 µm across but only 10 to 20 nm thick at its center.
The Golgi is the cell’s sorting and shipping center. Vesicles from the endoplasmic reticulum arrive at the receiving side, the cis face. The Golgi modifies the proteins, adding sugar chains and phosphate tags that work as destination labels. The shipping side, the trans face, then releases them in secretory vesicles. In plant cells the Golgi also makes the polysaccharides of the cell wall.
Watch the vesicles in the model. They bud from the Golgi and travel along microtubules toward the plasma membrane. Each microtubule is about 25 nm across.
Endoplasmic reticulum: rough and smooth
The endoplasmic reticulum (ER) is a network of membrane sheets and tubes joined to the nuclear envelope. It comes in two kinds, and the model colors them differently.
The rough ER is studded with ribosomes on its outer surface. Those ribosomes make proteins and feed them into the ER lumen, where the proteins fold and pick up side chains. The rough ER also makes phospholipids for the cell’s membranes. It is abundant in protein-secreting cells such as liver cells. Its sheets are about 60 to 100 nm thick.
The smooth ER has no ribosomes. Its tubes, also about 60 to 100 nm across, make carbohydrates, lipids and steroid hormones, detoxify medications and poisons, and store calcium ions. In muscle cells a specialized form stores the calcium that triggers contraction.
Nucleus, ribosomes and the cytoskeleton
The nucleus is a double-membrane compartment, 5 to 10 µm across in a mammalian cell. It holds about 2 m of DNA, packed with proteins as chromatin. RNA copies of genes leave through about 2,000 nuclear pores, and the nucleolus inside assembles ribosome subunits. For the molecule itself, open the DNA 3D model.
The cytoskeleton has three fibres. Actin is the thinnest at 7 nm. Intermediate filaments measure 8 to 10 nm and bear tension. Microtubules are the widest at about 25 nm. A centrosome, built around two centrioles, organizes the microtubules in animal cells.
Eukaryotic cell vs prokaryotic cell
A eukaryotic cell keeps its DNA in a nucleus and has membrane-bound organelles. Animals, plants, fungi and protists are made of eukaryotic cells. A prokaryotic cell has no nucleus and no membrane-bound organelles. Bacteria and archaea are prokaryotes. Both kinds of cell share four parts: a plasma membrane, cytoplasm, DNA and ribosomes.
| Feature | Animal cell (eukaryote) | E. coli (prokaryote) |
|---|---|---|
| Nucleus | Yes, inside a double-membrane envelope | No. DNA lies in a nucleoid |
| Size | 10 to 100 µm across | 1 to 3 µm |
| Ribosomes | 80S | 70S |
| Membrane-bound organelles | Many | None |
| DNA | Linear chromosomes | One circular chromosome, plus plasmids |
| Cell wall | None | Peptidoglycan wall and an outer membrane |
| Makes ATP in | Mitochondria | The plasma membrane |
| Division | Mitosis | Binary fission |
The size gap is large. A HeLa cell is about 17 µm across, so eight or nine E. coli laid end to end would span it. Turn on Compare to see that ratio, then switch on the magnify option to enlarge the bacterium ten times. The ribosomes also differ in type: bacterial 70S ribosomes are lighter than eukaryotic 80S ribosomes, which is why many antibiotics block bacterial ribosomes and leave yours alone.
More on each group: eukaryotic cells, prokaryotic cells and plant cells vs animal cells.
Prokaryotic cell structure: the E. coli bacterium
Escherichia coli is a rod-shaped, gram-negative bacterium about 1 µm wide and 2 to 3 µm long. Everything happens in one compartment, so the model needs fewer parts than the animal cell. Work from the outside in:
- The capsule is a sticky polysaccharide coat that helps the cell attach to surfaces. Not every strain makes one.
- The outer membrane is the second membrane of a gram-negative cell, about 13 nm thick.
- The cell wall is a single thin layer of peptidoglycan, about 6 nm thick. Peptidoglycan is found only in bacteria. Archaea build their walls from a similar polymer called pseudopeptidoglycan.
- The periplasm is the gel-filled gap between the two membranes, about 11 to 15 nm wide.
- The nucleoid holds a circular chromosome of about 4.6 million base pairs and fills half to three-quarters of the cytoplasm.
- Ribosomes, about 20,000 per cell, float free. Inclusion granules store nutrients such as glycogen.
- A flagellum spins like a propeller. Pili pass DNA between cells, and fimbriae help the cell stick.
For other organisms in this group, see examples of archaea and types of bacterial reproduction.
What the model simplifies
The model is accurate in structure and exaggerated in scale, so that you can see and click every part.
- Thickness is exaggerated. Ribosomes, cytoskeleton fibres and membranes are drawn thicker than they are, because a true 7 nm fibre would be invisible at this scale.
- Counts are reduced. A real cell holds hundreds or thousands of mitochondria, lysosomes and ribosomes. The model draws a few of each.
- E. coli is shown 10 times larger than its true size next to the animal cell, so it fills the screen. Compare mode shows the true ratio.
- The cell is one example. Real animal cells vary in shape, and a neuron, a muscle cell and a red blood cell look nothing alike. The model shows a generic cell.
The structure-level facts, such as which membranes surround which parts, follow standard textbook biology. Every size on the cards comes from the sources listed at the end of this page.
Frequently asked questions
What is the difference between prokaryotic and eukaryotic cells?
A eukaryotic cell has a nucleus and membrane-bound organelles. A prokaryotic cell has neither: its DNA lies in a nucleoid and its chemistry runs in a single compartment. Eukaryotic cells are also larger, typically 10 to 100 µm across against 0.1 to 5 µm for prokaryotes, and they have 80S ribosomes where prokaryotes have 70S.
Do bacteria have mitochondria?
No. Bacteria are prokaryotes and have no membrane-bound organelles. They make ATP at their plasma membrane. Mitochondria are thought to descend from bacteria that once lived inside a larger cell.
Why are mitochondria called the powerhouse of the cell?
Mitochondria make most of the ATP that a cell spends as energy. The folds of the inner membrane give the ATP-making machinery a large surface, and energy-hungry cells such as liver cells carry well over a thousand mitochondria.
What organelles do animal cells lack compared with plant cells?
Animal cells have no cell wall, no chloroplasts and no large central vacuole. Animal cells have two things that most plant cells lack: a centrosome with centrioles, and lysosomes. Plant cells do their digesting in vacuoles.
How big is a cell?
Eukaryotic cells are 10 to 100 µm across. A human red blood cell is about 8 µm, and a HeLa cell is about 17 µm. Prokaryotes are 0.1 to 5 µm, and E. coli is about 2 µm long and 1 µm wide.
What is the cell membrane made of?
A phospholipid bilayer with embedded proteins. The two lipid layers are about 5 to 10 nm thick in total.
Is the 3D cell model to scale?
Not exactly. The organelles are in correct proportion to each other within a cell, but thin structures such as membranes and filaments are drawn thicker than true scale. Compare mode shows the true size ratio between the two cells.
Related on 33Science
- DNA 3D model
- Atom 3D model
- Facts about DNA
- Types of cellular metabolism
- Photosynthesis vs cellular respiration
- Types of microscopes
- Biology topics
Sources
- OpenStax. Biology 2e, chapters 4.1 to 4.5 (cells, prokaryotic cells, eukaryotic cells, the endomembrane system and the cytoskeleton). Licensed CC BY 4.0.
- OpenStax. Microbiology, chapter 3.3, Unique characteristics of prokaryotic cells.
- Milo R, Jorgensen P, Moran U, Weber G, Springer M. BioNumbers, the database of key numbers in molecular and cell biology, bionumbers.hms.harvard.edu. Each card on the model cites its BioNumbers IDs (BNIDs).
- Architecture of the Mammalian Golgi, PubMed Central (cisterna counts and dimensions).
Credits and sources
- Cell data on the part cards: OpenStax Biology 2e, 4.2; OpenStax Biology 2e, 4.3; BioNumbers BNID 115568 (HeLa diameter); BioNumbers BNID 104208 (DNA length per nucleus); BioNumbers BNID 109953 (nucleus diameter); BioNumbers BNID 100001 (E. coli cell length); BioNumbers BNID 108187 (E. coli cell width); BioNumbers BNID 105779 (ribosomes per E. coli cell); OpenStax Biology 2e, 4.1; BioNumbers BNID 100787 (cell membrane thickness); BioNumbers BNID 103948 (erythrocyte membrane thickness); BioNumbers BNID 103944 (E. coli membrane thickness); BioNumbers BNID 104947 (E. coli envelope width); OpenStax Biology 2e, 4.5; BioNumbers BNID 103725 (HeLa cell volume); BioNumbers BNID 112088 (nucleoid share of cytoplasm); OpenStax Microbiology, 3.3; BioNumbers BNID 100483 (ribosome diameter); BioNumbers BNID 110369 (80S ribosome mass); BioNumbers BNID 107552 (HeLa ribosomes); BioNumbers BNID 107347 (HeLa ribosomes); BioNumbers BNID 100121 (70S ribosome diameter); BioNumbers BNID 102320 (70S ribosome size); BioNumbers BNID 109047 (ribosome RNA share); BioNumbers BNID 111130 (pores per nucleus); OpenStax Biology 2e, 4.4; BioNumbers BNID 113850 (envelope and plasma membrane thickness); BioNumbers BNID 103695 (vertebrate pore diameter); BioNumbers BNID 103696 (yeast pore diameter); BioNumbers BNID 110670 (yeast pores in G1); BioNumbers BNID 113849 (nucleolus radius); BioNumbers BNID 102981 (beads-on-a-string width); BioNumbers BNID 102982 (packed fibre width); BioNumbers BNID 102986 (turns around a nucleosome); BioNumbers BNID 111388 (ER sheet and tubule size); Architecture of the Mammalian Golgi (PMC); BioNumbers BNID 102727 (vesicle diameter); BioNumbers BNID 109239 (axon vesicle diameter); BioNumbers BNID 106123 (microtubule diameter); BioNumbers BNID 110892 (mitochondrion size); BioNumbers BNID 101798 (mitochondrion length); BioNumbers BNID 105783 (mitochondria per hepatocyte); BioNumbers BNID 105782 (mitochondrial volume fraction); BioNumbers BNID 109409 (mitochondria per HeLa cell); BioNumbers BNID 106072 (lysosome diameter); BioNumbers BNID 106074 (lysosomal pH); BioNumbers BNID 117094 (lysosomes per cell); BioNumbers BNID 106729 (peroxisome diameter); BioNumbers BNID 113108 (peroxisome diameter); BioNumbers BNID 105741 (centriole size); BioNumbers BNID 101960 (microtubule growth time); BioNumbers BNID 101963 (microtubule growth rate); BioNumbers BNID 109237 (microtubule diameter); BioNumbers BNID 106126 (virion speed on microtubules); BioNumbers BNID 111734 (enterocyte microvilli length); BioNumbers BNID 111733 (microvilli per enterocyte); BioNumbers BNID 103717 (HeLa microvilli length); BioNumbers BNID 102481 (HeLa microvilli number); BioNumbers BNID 111126 (small intestine surface area); BioNumbers BNID 108065 (capsule fibril length); BioNumbers BNID 108062 (capsule size); BioNumbers BNID 100015 (outer membrane thickness); BioNumbers BNID 105385 (peptidoglycan thickness); BioNumbers BNID 105383 (peptidoglycan thickness); BioNumbers BNID 102997 (peptidoglycan layers); BioNumbers BNID 100016 (periplasm thickness); BioNumbers BNID 109174 (periplasm width); BioNumbers BNID 100010 (periplasm volume share); BioNumbers BNID 107851 (periplasm volume share); BioNumbers BNID 100269 (E. coli genome size); BioNumbers BNID 107010 (chromosome length); BioNumbers BNID 101852 (nucleoid radius); BioNumbers BNID 107009 (nucleoid volume); BioNumbers BNID 105306 (pSC101 copy number); BioNumbers BNID 105303 (pBluescript copy number); Plasmid DNA (ScienceDirect topic overview); BioNumbers BNID 100095 (flagellum length); BioNumbers BNID 100096 (flagellum diameter); BioNumbers BNID 100097 (protofilaments); BioNumbers BNID 106205 (conjugative pili per cell); BioNumbers BNID 100104 (pilus length); BioNumbers BNID 100105 (pilus diameter); BioNumbers BNID 101473 (pili or fimbriae per cell); BioNumbers BNID 100107 (fimbrin per fimbria); Molecular Structure of Glycogen in Escherichia coli (Biomacromolecules).
- The 3D model, labels and poster image are by 33Science, licensed CC BY 4.0. Credit 33Science and link to this page.